Health
According to new studies, cancer patients frequently respond better to less extensive treatment.
Physicians announced at the largest cancer conference in the world that patients’ lives can be improved without compromising outcomes by reducing treatment for three types of cancer.
It’s a part of a long-term trend investigating if cutting back on radiation, chemotherapy, or surgery can improve patient outcomes and lengthen life. The most recent research included Hodgkin lymphoma, ovarian, and esophageal cancer.
The goal of cancer research thirty years ago was to accomplish more, not less. One grim example is bone marrow transplants and high dosages of chemotherapy that drove people with advanced breast cancer to the verge of death. The method wasn’t any more effective than chemotherapy, and the patients experienced harm.
Researchers are now questioning, “Do we need all that treatment that we have used in the past?” in an effort to optimise cancer care.
Dr. Tatjana Kolevska, medical director of the Kaiser Permanente National Cancer Excellence Programme, who was not involved in the current research, stated that this is a subject “that should be asked over and over again.”
Doing less is frequently possible due to better medications.
As Dr. William G. Nelson of the Johns Hopkins School of Medicine put it, “the good news is that cancer treatment is not only becoming more effective, it’s becoming easier to tolerate and associated with less short-term and long-term complications.” Nelson was not involved in the recent study.
Over the weekend, at a symposium in Chicago hosted by the American Society of Clinical Oncology, studies illustrating the trend were deliberated. The highlights are as follows:
OVARIAN CANCER
French researchers discovered that while undergoing surgery for advanced ovarian cancer, it is safe to leave lymph nodes that seem healthy intact. Results for 379 patients were compared in the study; half had their lymph nodes removed, and the other half did not. The patients’ lives did not differ after nine years, and those who underwent less-invasive surgery experienced fewer aftereffects, such as the requirement for blood transfusions. The French National Institute of Cancer provided funding for the study.
ESOPHAGEAL CANCER
This German study examined 438 patients with an esophageal cancer that is surgically treatable. The oesophagus, the tube that transports food from the throat to the stomach, was surgically repaired and chemotherapy was part of the standard treatment regimen for the other half. Half received a different strategy that also involves radiation. Both methods are regarded as conventional. Which one a patient receives may vary depending on where they receive care.
Three years later, 57% of patients who received chemotherapy and surgery and 51% of patients who received chemotherapy, surgery, and radiation were still alive. The study was financed by the German Research Foundation.
HODGKIN LYMPHOMA
When two different chemotherapy regimens for advanced Hodgkin lymphoma were compared, it was discovered that the less rigorous treatment was more successful in curing the blood cancer and had fewer adverse effects.
Compared to 91% of individuals who had the more intensive treatment, 94% of those who received the less harsh chemotherapy were able to control their condition after four years. The experiment, which was supported by Takeda Oncology, the manufacturer of one of the medications used in the milder chemotherapy that was investigated, involved 1,482 participants from nine countries: Germany, Austria, Switzerland, the Netherlands, Denmark, Sweden, Norway, Australia, and New Zealand.
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Fashion
In a lavender Manish Malhotra saree, Hania Aamir sports her most gorgeous ethnic ensemble to date. View its astounding cost.
Hania Aamir serves stunning ethnic fashion inspiration in lavender Manish Malhotra tissue saree. Wondering how much it costs? Scroll down for all the details.
Hania Aamir is leaving fashion lovers spellbound with her stunning ethnic diaries. The Pakistani actor has been rocking back-to-back traditional outfits by Indian designers, turning her Insta feed into a goldmine of fashion inspo. For her latest look, the 27-year-old slipped into six yards of grace and looked straight out of a royal fairytale. Let’s break down her saree look and steal some style tips for your ethnic wardrobe. Hania Aamir stuns in lavender saree
On Monday, Hania took to Instagram and uploaded a series of gorgeous snaps accompanied by the caption “gave mermaid.” Draped in a dreamy lavender saree, the star looked absolutely breathtaking while serving some striking glam poses. Let’s take a moment to soak in her ethereal beauty.
Hania’s saree is crafted from luxurious tissue fabric and features intricately embroidered borders, showcasing stunning zari work, beads, and sequin detailing throughout. Draped to perfection, she let the pallu elegantly cascade from her shoulder, adding a regal charm to her look. She teamed it up with a matching embroidered blouse, complete with delicate handmade tassels at the back.
How much does her saree cost?
Can’t stop swooning over Hania’s gorgeous saree? We’ve got all the details you need to add this stunner to your collection. Her six yards is straight from the shelves of ace designer Manish Malhotra and is priced at ₹3,95,000.
Hania accessorised her ethnic look with dazzling diamond jewellery, including statement drop earrings, a chic choker necklace, a sleek bracelet, and a stunning ring adorning her finger. Her dewy makeup featured shimmer eyeshadow, winged eyeliner, mascara-coated lashes, blushed cheeks, a luminous highlighter, and glossy nude lipstick. With her long, luscious tresses left loose in a side partition, she perfectly finished off her look.
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Health
Knowing the main distinctions and risks between HMPV and COVID-19.
As India logs 5 cases of HMPV, here’s all you need to know about how human metapneumovirus is different from Covid-19 and warning signs to watch out for.
HMPV virus is not a novel virus – it was first isolated in 2001 by Van den Hoogen and her colleagues in Netherlands in the nasopharyngeal secretions of children with respiratory tract infections. The virus was named human metapneumovirus because it was a metapneumovirus that used humans as a host.
The human metapneumovirus (hMPV) is a common respiratory virus that typically causes mild cold-like symptoms. Studies show it has circulated in human populations since the 1970s, though it was first identified by scientists in 2001.
The virus accounts for 4-16% of acute respiratory infections globally, with cases usually peaking between November and May. While most adults have developed immunity through previous exposure, hMPV can cause more severe symptoms in infants encountering it for the first time and in people with weakened immune systems.
In an interview with HT Lifestyle, Dr Sangeeta V Budur, Consultant – Paediatrics and Paediatric Intensive Care at Aster RV Hospital, shared, “It is known to cause a range of illnesses from mild upper respiratory infections to severe pneumonia , bronchiolitis and acute respiratory distress syndrome. About 5 to 25% of the acute pediatric lower respiratory tract infections are associated with HMPV. The viral outbreaks peak in winter and spring season in northern hemisphere and June and July in southern hemisphere.”
Who are the vulnerable population?
Dr Sangeeta V Budur revealed, “No age group is immune to the virus, reinfection occurs throughout the life but subsequent infections are mild. Infants, children under 2 years, elderly, Immuno-compromised persons or those with underlying chronic medical conditions are more vulnerable to the severe disease. The HMPV infection appears to be ubiquitous, as virtually all children are exposed by the age of 5 years.”
How does it spread?
According to Dr Sangeeta V Budur, just like any other respiratory illness, HMPV spread via respiratory droplets i.e. coughing, sneezing or contact with infected secretions.
How is it different from Covid -19 ?
Dr Sangeeta V Budur informed, “Both viruses cause minor respiratory symptoms in most of the infected people but Covid -19 has a broader spectrum of symptoms involving multiple body systems and a higher potential for systemic complications. The comparison between the two viruses is difficult though the spread is through the droplets via the respiratory route in both. HMPV is less transmittable and has less severe symptoms as compared to Covid-19.”
What are the symptoms of HMPV virus?
Dr Sangeeta V Budur answered, “Most of the symptoms are mild flu like lasting 5- 7 days requiring outpatient visits. But in children under five , HMPV is responsible for 3-10% of hospital admissions. Among the hospitalized children high grade fever, respiratory distress, wheezing rare the predominant symptoms.”
What are the respiratory illnesses caused by HMPV?
As per Dr Sangeeta V Budur, HMPV is mainly known to cause upper respiratory tract infection in most of the children but bronchiolitis, severe pneumonia, acute respiratory distress syndrome in few which require hospitalization, oxygen therapy including mechanical ventilation.
How to diagnose HMPV infection?
Dr Sangeeta V Budur highlighted, “Diagnosing HMPV based solely on symptoms is difficult, as it mimics other respiratory infections like respiratory syncytial virus( RSV) and influenza. PCR testing on nasopharyngeal secretions for detecting HMPV RNA is the gold standard. In India, surveillance systems like ICMR and the Integrated disease surveillance Programme( IDSP) regularly test for respiratory viruses including HMPV.”
What are treatment options for HMPV?
There is no specific antiviral drug available. Dr Sangeeta V Budur said, “Treatment is mainly symptomatic and supportive with antipyretics and antihistaminics. Hospitalised children may need oxygen therapy , nebulizations and rarely mechanical ventilation among the severely infected.”
What are preventive measures for HMPV?
As of now there is no targeted therapy/vaccine available for HMPV. Dr Sangeeta V Budur suggested, “Proper hand hygiene – washing hands frequently with soap and water for at least 30 seconds. Cough etiquette such as covering the nose and mouth while sneezing and coughing, wearing a mask can limit the spread of the virus. Avoiding close contact with infected individuals, regularly disinfecting touched surfaces are additional measures.”
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Health
HMPV: Bengaluru Hospital’s 8-month-old is said to have tested positive.
The infant and its family had no history of recent travel and did not show any symptoms of concern.
The Indian Council of Medical Research (ICMR) has confirmed two cases of Human Metapneumovirus (HMPV) in Karnataka, identified through routine surveillance for respiratory viral pathogens.
As part of ongoing efforts to monitor respiratory illnesses nationwide, the ICMR detected these two cases. One case involves an eight-month-old male infant in Bengaluru, whose sample collected on January 2 tested positive for HMPV. According to sources in the BBMP (Bruhat Bengaluru Mahanagara Palike) health department, the infant and their family had no recent travel history and showed no concerning symptoms.
The second case involves a three-month-old female infant with a history of bronchopneumonia, who tested positive for HMPV after being admitted to Baptist Hospital in Bengaluru. She has since been discharged and is recovering, the Union Health ministry said.
HMPV primarily affects children and is known to be present in about 0.7 per cent of flu cases globally. However, Karnataka health officials have stated that they lack detailed information on the specific strain in question.
Responding to the developments, Karnataka Health Minister Dinesh Gundu Rao said on Monday, “This is not India’s first case. The virus has been around for years, but this could be a new strain. More details are needed to ascertain that.”
What is HMPV?
Human Metapneumovirus (HMPV) has recently garnered attention due to videos and reports circulating on social media, suggesting that hospitals in China are overwhelmed by a surge in respiratory illnesses, including HMPV. Posts also claim that outbreaks of multiple viruses, including HMPV, influenza A, Mycoplasma pneumoniae, and COVID-19, have contributed to overcrowding in both hospitals and cemeteries.
HMPV, first identified in 2001 by researchers in the Netherlands, is a significant cause of acute respiratory infections, according to the American Lung Association. The virus primarily spreads through close contact with infected individuals, either through respiratory droplets from coughing or sneezing, or by touching contaminated surfaces such as doorknobs or toys.
In the United States, HMPV typically circulates more frequently during the winter and spring months, overlapping with other respiratory infections like Respiratory Syncytial Virus (RSV) and the flu.
Symptoms of HMPV
The symptoms of HMPV can vary in severity and commonly include cough, fever, runny or stuffy nose, and sore throat. Some individuals may also experience wheezing and shortness of breath (dyspnea). In certain cases, a rash may develop as part of the infection.
According to Google Trends, searches for ‘HMPV virus symptoms’ surged on Sunday and peaked on Monday. Related queries included ‘fatigue,’ ‘fatigue meaning,’ ‘HPV virus cases in India news,’ ‘nasal congestion,’ and ‘HMPV virus in Bangalore’. Most searches originated from Karnataka, Telangana, and Andhra Pradesh. The spike followed reports of two HMPV cases detected in Karnataka on Monday.
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