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Growing number of whooping cough infections in the US and Europe raises concerns among medical professionals

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Cases of whooping cough, also known as pertussis, are increasing in the US and Europe. Experts claim they don’t know why. Health professionals throughout the European continent began to notice something strange in the winter of 2023. Pertussis, another name for whooping cough, was becoming more common. Furthermore, it wasn’t limited to Europe. Additionally, US health officials started to record an increase in instances of whooping cough. Furthermore, the number of cases in the UK has reached its highest level in twenty years.

The number of cases in Europe had increased by March 2024 compared to the previous ten years (the European Centre for Disease Prevention and Control (ECDC) did not issue numbers before to 2011). In Europe, reports of 32,000 instances were received between January and March of 2024. The ECDC estimates that 38,000 cases of pertussis are reported annually on average throughout Europe. Whooping cough incidences could tenfold rise in 2024 compared to a normal year if the current trend persists.

The bulk of instances in Europe occurred among newborns, a population for which whooping cough can be fatal, according to data from the ECDC’s most recent study on the matter. Ten to fourteen-year-olds accounted for the second-highest reported case group.

Paul Hunter, an English professor of medicine at the University of East Anglia, said DW that these numbers should be regarded cautiously. He indicated there might be more cases than were recorded. Babies are significantly more likely than other demographic groups to be diagnosed with whooping cough because they are at such a high risk of contracting it. It’s possible that a large number of elderly people suffer undiagnosed whooping cough as well.

However, Hunter added that there’s a chance that a similar spread is occurring. According to him, doctors may be more inclined to diagnose cases now that they are aware of whooping cough than they were in the past, which could further skew the statistics.

Use of vaccines during pregnancy

The symptoms of whooping cough initially resemble a cold. A low-grade fever, runny nose, sneezing, and sporadic coughing are possible symptoms for patients. However, after a few weeks of having pertussis, coughing fits that sound like a high-pitched “whoop” may begin. While minor cases might not have the accompanying whoop, the sickness is most severe in youngsters and newborns. Up to ten weeks may pass during this phase.

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Say experts, they have no idea why there is a spike in instances. Like most infectious illness outbreaks, this one might be caused by a number of unrelated events happening all at once. It might be the outcome of the consistent drop in pertussis vaccinations given to expectant mothers throughout Europe, in addition to a general reduction in infant vaccination rates. This would provide some insight into the newborns’ situation. If their mothers did not receive a vaccination throughout their pregnancies, the newborns have no defence against whooping cough.

“​​You only start vaccinating children against whooping cough at about eight weeks,” Hunter stated. “And the majority of the most serious illnesses typically occur earlier than that.” The May ECDC report states that rates of pertussis immunisation during pregnancy vary greatly around the European continent. In 2023, 88% of expectant Spanish citizens received a pertussis vaccination. Just 1.6% of people in the Czech Republic, where instances of pertussis have sharply increased, had received the vaccination in the same year. Pregnant women’s uptake in the UK has decreased over the last ten years, going from over 70% in 2016 to roughly 60% in 2023.

The role of COVID
Furthermore, the increase may have resulted from a decline in population-wide immunity following the COVID-19 pandemic, as reported by health experts. The pandemic’s stringent measures to prevent SARS-CoV-2, such as mask use, hand washing, and limiting social interaction in public areas, resulted in historically low levels of flu and strep infections.

Cases have resumed growing since the pandemic’s termination. However, according to Hunter, that is insufficient to account for the sharp rise in whooping cough cases. This is because, before to the pandemic, whooping cough was not a serious illness in the general population. It was uncommon, but it was there. Not the flu, though. In the years after the pandemic, the number of flu cases may have doubled.

vaccination against pertussis

According to specialists, the whooping cough vaccines themselves may be the third potential aggravating reason. Midway through the 20th century, developed nations including the US, Canada, and portions of Europe saw the introduction of the first pertussis vaccination. It has unfavourable side effects despite being incredibly powerful. The ensuing dramatic decline in uptake resulted in outbreaks during the 1970s and 1980s.

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Countries started rolling out second-generation pertussis vaccines in the late 1990s and early 2000s. Instead of using a full cell, this new version used an acellular shot. It was somewhat less successful than the first vaccine, providing immunity for a shorter duration, even though it did not cause the side effects.

What should I do next?
According to Andrew Preston, a professor and whooping cough expert at the University of Bath in the UK, the increase in instances raises challenging questions for medical professionals treating whooping cough, as reported by DW. He stated that while using boosters to reduce spread would be a possibility, “it’s not entirely clear how often you can boost without losing effectiveness.”

Or are we content with the current state of affairs, where everyone else only has to occasionally deal with a persistent cough as long as we can prevent newborns from being seriously sick and dying? Preston mentioned that there are pertussis vaccinations available now, some of which have the potential to confer “far superior” immunity in comparison to the two now in use.

But he said that it would be difficult to include these doses into the present immunisation regimen. In the UK and much of Europe, the pertussis vaccination is given in combination with five other vaccines in a single shot; therefore, adding a new vaccine would need redesigning the existing combination vaccine. “You’d have to reformulate all those other vaccines, and that’s just a monstrous task,” Preston added.

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Meaty rice’: what is it? A sustainable protein that will revolutionise the world’s food supply

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Scientists from South Korea are hoping to transform global eating habits by introducing individual rice grains with grown cow cells in a tiny lab in Seoul. Team leader and professor Hong Jin-kee thinks his new so-called “meaty rice” might become an ethical and environmentally sustainable way for people to receive protein, from preventing famines to feeding astronauts in space.

The meal, which is made without using any animals, has the appearance of a typical bowl of rice (although pink), but because it contains beef muscle and fat cell culture, it has a subtle buttery scent. Hong, of Yonsei University in Seoul, stated that “we can obtain animal protein without the slaughter of livestock” by using cultured meat.

Due to environmental worries about greenhouse gas emissions from animal husbandry and ethical qualms about industrial livestock rearing, businesses all over the world have been looking to commercialize meat substitutes like plant-based or cultured meat. With a background in organoids and biomedical sciences, Hong decided to focus his research on rice because it’s the most popular grain in Asia for protein.

Currently, this can be a laborious process: a typical rice grain is individually injected with beef cells, coated with fish gelatin to aid in adhesion, and then cultivated in a petri dish for up to 11 days. According to Hong, rice has a “slightly porous structure,” and after the beef cells are injected, the grain provides “an ideal structure for cells to grow uniformly from the inside out”.

carbon footprint
Compared to ordinary rice, Hong’s “meaty” rice has 7% more fat and 8% more protein. Although Hong and his colleagues are still figuring out how to scale the procedure, he intends to have their invention certified as emergency relief food for two African nations. “For those who are limited to… just one meal a day, a slight increase in (protein content), even by just a few percent, becomes incredibly important,” he stated.

Although it hasn’t authorised any meat that has been grown for human consumption, South Korea declared in 2022 that it would invest millions of dollars in a “foodtech” fund and designated cell-cultured meat as a top research priority. Singapore and the United States sell meat that has been raised.  but Italy banned it last year citing a need to safeguard its livestock industry. Some scholars say potential ethical concerns with cultured meat include the sourcing of the initial animal cells.

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It’s hard to be “certain about the safety of the serum used in culture media, and the antibiotics and hormones added during the culturing process” , Former Seoul National University emeritus professor Choi Yoon-jae,

By removing the need to produce and farm animals, Hong’s team’s hybrid rice approach greatly reduces the carbon footprint of protein. He calculates that it releases 6.27 kilogrammes (13.8 pounds) of carbon dioxide for every 100 grammes (3.5 ounces) of protein produced, which is eight times less than standard beef production.

Would you consume it?
According to Neil Stephens, a technology and society lecturer at the University of Birmingham, cultured meat has long been “presented as a climate solution compared to traditional livestock”. However, he pointed out that the industry faces difficulties, such as the requirement to be “produced at scale, and cheap, with low energy needs and environmentally friendly inputs,”

“The ‘meaty’ rice might have an advantage over some other cultured meat products” , because it’s a hybrid item that involves “mixing animal cells with plant material — the rice — making cheaper and less energy intensive,” he stated. Nevertheless, it would still need to persuade people to eat it and demonstrate its environmental merits on a large scale. Both could provide difficulties.”

By 2040, only 40% of the world’s meat consumption would come from conventional sources, according to global firm AT Kearney, upending the whole meat sector. According to a 2019 article, “Products such as milk, egg white, gelatin, and fish can be created with similar technology.” Hong is adamant that biotechnology has the power to improve human nutrition consumption.

For instance, he explained, eating lab-grown beef made exclusively of muscle cells rather than fat could help an elderly person suffering from sarcopenia, or muscle loss. He stated that “more biological information becomes available and we need to meticulously control our food” as a new era approaches.

He added that this might imply that a  future AI-infused kitchen could assess a person’s health through a blood analysis, then instruct a robot to prepare the most suitable breakfast.

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World Blood Donor Day 2024: 5 reasons to give blood and information about its health advantages

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World Blood Donor Day 2024: Donating blood is a noble task, and it also comes with multiple health benefits. Blood transfusion is done to treat multiple health disorders such as anemia, cancer, etc. People are urged to donate healthy blood as it helps in a steady supply of blood for the healthcare industry. Every year, World Blood Donor Day is celebrated on June 14 to establish the importance of donating blood and how it helps in patient treatment. However, donating blood is a double bonanza–it helps the one donating blood, as well as the one receiving it. As we celebrate the important day today, here are a few things that we should know.

Unexpected health advantages of blood donation:
Promotes heart health:
The act of giving blood improves cardiovascular health. It also lessens blood viscosity, which helps to lower the risk of strokes and heart attacks. Donating blood contributes to maintaining a healthy blood supply, which lessens cardiac strain.

decreases iron stores:

Hemochromatosis, a disorder that can harm organs like the liver and heart, is brought on by an excessive amount of iron in the blood. Regular blood donation reduces extra iron, which is beneficial to general health.

Creation of new blood cells:

The body attempts to make up for blood lost after donating. This promotes the body’s ability to create new cells and carry out tasks efficiently in addition to aiding in the development of new blood cells.

Free health screening:

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It is required to undergo a basic health examination, which includes measuring blood pressure, body temperature, pulse, and haemoglobin levels, prior to donating blood. This can assist us in better understanding our bodies and, if necessary, addressing any health issues that may arise.

enhances mental health
We get a psychological lift and feel better when we know that the blood we have donated may save a life or aid someone in need.

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Women are more vulnerable than men to gonorrhea due to rising antibiotic resistance.

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Don’t engage in sexual activity. It is “the only way to completely avoid STIs,” according to public health organizations. Avoid engaging in any oral, anal, or vaginal sex.

It is a sobering piece of wisdom. However, it also makes perfect sense when you look at the most recent data on the spread of antimicrobial resistance (AMR) and bacterial STIs, such as gonorrhea, from the European Centre for Disease Prevention and Control (ECDC).

Antibiotics including azithromycin, ceftriaxone, and cefixime are frequently used in medicine to treat gonorrhea, but their efficacy is declining. And that might be a factor in the rise in gonorrhea infections and STI cases in general throughout Europe, if not the world.

In a study released on June 10, 2024, the ECDC stated that there were 70,881 confirmed cases of gonorrhea in 28 EU/EEA (European Union/European Economic Area) nations in 2022, a 48% increase from the previous year.

AMR is one reason why antibiotics across the board — whether it’s for STIs or an earache — are failing public health efforts. Either we use them too much, or we don’t bother to take all the pills, with the result that bacteria are able to build up a resistance to many of our “go-to” drugs of the past 100 years.

Gonorrhea: What is it?
The Neisseria gonorrhoea bacteria is the cause of gonorrhea. It may impact the esophagus, rectum, or genitalia. Infections are common in young persons (ages 15 to 24).

Women are more likely than males to get an infection since diagnosis is more difficult for them. Women also frequently don’t have symptoms, and when they do, they are typically minor and can be confused for another vaginal or bladder infection. particularly expectant mothers, who may transmit STI infections to their fetus. Undiagnosed sexually transmitted infections can cause pregnancy problems in women or cause infertility.

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However, men do experience symptoms, such as painful or enlarged testicles, a burning feeling when peeing, and a discharge that can be white, yellow, or green.

However, this is less common in women than it is in them. Teodora Elvira Wi, who oversees the global HIV, hepatitis, and STI programs at the World Health Organization in Geneva, stated that women must be given priority because they are asymptomatic.

“We need opportunities for women to be screened for STIs, and especially people at higher risk, people who have multiple partners and sexually active adolescents,” stated Wi.

Concerning’ antimicrobial resistance to popular medications for gonorrhea
In the ECDC paper, 4,396 gonorrhea samples (also known as “isolates”) from 23 different nations were analyzed. These samples were taken in 2022.

They discovered that “isolates resistant to azithromycin increased significantly to 25.6%, compared to 14.2% in 2021.”

Since azithromycin and ceftriaxone are frequently used together, the ECDC deemed this result to be “particularly concerning.”

Ciprofloxacin resistance rose as well, though not as dramatically: in 2022, 65.9% of isolates showed resistance, up from 62.8% in 2021.

Cefixime resistance remained “low at 0.3%.”

All things considered, the World Health Organization’s data from other regions—Africa and Asia, for example—reflects the ECDC figures.

According to Wi, 73 countries worldwide have reported antimicrobial resistance data in gonorrhea. “Antimicrobial resistance is not the only cause [there], but in countries where antimicrobial resistance is even higher than in Europe, it is contributing to the increase in bacterial STIs,” Wi added.

Pharyngeal (throat) gonorrhea was on the rise in 2022, according to ECDC data, although genital and anorectal gonorrhea cases stayed steady.

How to reduce STI transmission
According to WHO data from 2020, 374 million new cases of syphilis, gonorrhea, chlamydia, and trichomoniasis among individuals aged 15 to 49 occur worldwide each year. The increasing incidence of STI cases was attributed by the WHO to the following factors:

An increase in risky sexual conduct, such as the usage of fewer condoms and a rise in the number of casual and committed relationships

Socioeconomic factors and asymptomatic infections; biological considerations

Due to underfunding of services, there is a paucity of STI services, poor access to STI services, and a shortage of diagnostic test instruments.

Stigma: As a result of stigma, STI services and research are underfunded, and patients are less likely to seek treatment.

In public health initiatives to limit STIs, addressing and/or reversing these variables would be a smart place to start.

Wi advised against quitting entirely, saying that having sex should be accompanied by education. “Have sex, have pleasure in sex, make it a voluntary thing, do it for your sexual well-being and protect yourself the way you protect yourself from other infections,” she stated.

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