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Study Reveals Structural Alterations Brought on by Osteoarthritis

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Global, July 7, 2023 – Osteoarthritis, a common degenerative joint disease affecting millions of people worldwide, has long been a subject of scientific interest. In a recent breakthrough, a comprehensive study has shed light on the structural alterations that occur in the joints affected by osteoarthritis. The findings provide valuable insights into the disease’s progression and may pave the way for improved diagnosis and treatment strategies.

Led by a team of researchers from renowned institutions, the study aimed to examine the intricate changes that take place within the affected joints of individuals with osteoarthritis. The research focused on analyzing the molecular, cellular, and tissue-level alterations, providing a multi-dimensional understanding of the disease.

Through extensive experimentation and analysis, the researchers discovered several key structural alterations associated with osteoarthritis. These findings have the potential to transform the way osteoarthritis is diagnosed, monitored, and treated. Some of the notable discoveries include:

Cartilage Degeneration: The study confirmed the progressive degradation of cartilage, the protective tissue that cushions the joints. It identified specific molecular markers and cellular mechanisms involved in cartilage breakdown, contributing to a better understanding of the disease’s underlying processes.

Synovial Inflammation: The researchers observed significant inflammation in the synovium, the thin membrane lining the joint cavity. The inflammation was linked to the release of certain enzymes and cytokines, which further contributed to joint damage and pain.

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Bone Remodeling: The study revealed alterations in the structure and composition of bone tissue near the affected joints. It identified abnormal bone remodeling processes, including increased bone resorption and impaired bone formation, leading to bone abnormalities and increased fracture risk.

Joint Capsule Changes: The researchers noted changes in the joint capsule, a fibrous structure that encloses the joint. These alterations included thickening and stiffening of the capsule, potentially contributing to joint stiffness and limited range of motion.

The comprehensive insights gained from this study have the potential to revolutionize the understanding and management of osteoarthritis. By identifying the specific structural alterations associated with the disease, researchers and clinicians can develop targeted interventions to slow disease progression, alleviate symptoms, and improve patients’ quality of life.

The findings also emphasize the importance of early detection and intervention in osteoarthritis. With a better understanding of the structural changes, healthcare professionals can develop more accurate diagnostic methods, enabling timely interventions that may prevent or delay further joint damage.

The researchers acknowledge that further studies are needed to validate and expand upon these findings. However, the current study lays a strong foundation for future research and holds great promise for advancements in the field of osteoarthritis.

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As scientists and medical professionals continue to delve deeper into the complex mechanisms of osteoarthritis, this study marks a significant step forward in unraveling the structural alterations associated with the disease. It brings hope for improved treatment strategies, ultimately aiming to enhance the lives of those affected by this debilitating condition.

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Congress leader: “Kangana Ranaut once said she likes beef.” BJP retaliates

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A significant controversy ensued following Congress leader Supriya Shrinate’s controversial social media post about actor-turned-politician Kangana Ranaut.

The Bharatiya Janata Party (BJP) has criticized Maharashtra Opposition and Congress leader Vijay Wadettiwar for claiming actor Kangana Ranaut’s post on Twitter about her beef preferences and the BJP’s decision to grant her a Lok Sabha election ticket.

Shaina NC, a BJP leader in Maharashtra, criticised Congress leader Vijay Wadettiwar’s comments and other ludicrous remarks made by Congress leaders. She stated that Wadettiwar’s actions, including granting Kangana Ranaut a ticket due to her beef consumption, are not the first time Congress has made such ludicrous remarks.

Shaina criticizes Congress social media in-charge Supriya Shrinate’s post against Ranaut, claiming that Shrinate’s comments and Randeep Surjewala’s discussion about Hema Malini’s attributes are anti-women, despite her age.

Shaina pledged that all women would participate in the voting process, and the results on June 4 would provide a “fitting answer to Congress.”

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The Prime Minister of India has ensured respect for women in various political parties, including Triple Talaq and Nari Shakti Vandan. If the Congress party lacks thought processes, the answer will be on June 4 when Indian women vote against the anti-woman Congress party.

Supriya Shrinate’s post that sparked controversy

Congress leader Supriya Shrinate’s controversial social media post about actor-turned-politician Kangana Ranaut, who received a BJP ticket from the Mandi constituency in Himachal Pradesh for the upcoming Lok Sabha election, sparked a massive controversy.

Kangana, in response to Shrinate’s post, emphasized that every woman deserves respect and dignity. She shared her 20-year career as an artist, which includes portraying various women, from naive girls in Queen to seductive spy in Dhaakad, goddesses in Manikarnika, demons in Chandramukhi, prostitutes in Rajjo, and revolutionary leaders in Thalaivii.

The Congress leader later revealed that someone with access to her social media accounts had posted objectionable content.

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PM Modi mocks Congress’s Lok Sabha election platform with the “imprint of Muslim League.”

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The Congress’s manifesto promised legal guarantees to MSP, a national minimum wage of ₹400 per day, and a nationwide caste census.

Prime Minister Narendra Modi criticized the Congress for its Lok Sabha election manifesto, claiming it was influenced by the Muslim League.

Modi criticized Congress’s manifesto, which he said reflected the same mindset as the Muslim League’s during the freedom movement, at a public meeting in Uttar Pradesh’s Saharanpur, where voters will vote in the first phase of Lok Sabha elections on April 19.

The Congress manifesto is largely influenced by the Muslim League, with any remaining parts being dominated by leftists.

The Prime Minister of India, Shri Narendra Modi, stated that the BJP government is committed to implementing government schemes that cater to all sections, castes, and communities.

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Modi’s attack comes after the Congress released its general election manifesto, emphasizing the ‘five pillars of justice’, including ‘Yuva Nyay’, ‘Naari Nyay’, ‘Kisaan Nyay’, ‘Shramik Nyay’, and ‘Hissedari Nyay’.

The Congress has pledged legal guarantees for the minimum support price, a national minimum wage of ₹400 per day, personal law reform, and a nationwide caste census.

Congress has announced that the MSP payable to farmer-sellers at procurement centers and APMCs will be directly credited to the farmer’s bank account digitally.

The grand old party announced that Congress will create and execute a robust import-export policy for agricultural commodities, prioritizing the protection of farmers’ interests and concerns.

The Lok Sabha elections will commence on April 19, with subsequent phases scheduled for April 26, May 7, 13, 20, 25, and June 1, with the vote counting scheduled for June 4.

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Cong selects ex-navyman Viriato Fernandes and former Union minister Khalap for Goa seats.

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Fernandes, a former navy captain from Kargil war, believes his candidacy represents the voice of every Goan and intends to bring it to Parliament.

The Congress party has announced its list of six candidates for both North and South Goa parliamentary seats in the upcoming Lok Sabha polls, announced by AICC general secretary K C Venugopal.

Congress has selected former Union minister Ramakant Khalap for the North Goa seat and former Navyman Viriato Fernandes for the South Goa seat.

Fernandes, a former navy captain from Kargil war, believes his candidacy represents the voice of every Goan and intends to bring it to Parliament.

Fernandes stated that the ticket is for all Goans and activists who have been protesting against the injustices of the BJP government, including issues like unemployment, inflation, industrialization of Goa’s coast through coal handling projects, and railway double tracking.

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The ruling party is threatening democracy by controlling independent institutions and using them to harass opposition figures, including former Jharkhand and Delhi chief ministers Hemant Soren and Arvind Kejriwal, in an unprecedented attack on democracy.

Fernandes, who previously lost to BJP’s Mauvin Godinho in the 2022 Goa legislative assembly polls, will face Pallavi Dempo, the first woman MP candidate named by the BJP, in the upcoming election.

Khalap represented the north Goa seat from 1996 to 1998, winning it for the Maharashtrawadi Gomantak Party.

Khalap, a seven-time MLA, is set to challenge BJP MP Shripad Naik for the North Goa seat, aiming to retain it for a sixth consecutive term.

The party has announced candidates for three seats in Madhya Pradesh and one for the Union Territory of Dadra and Nagar Haveli.

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Goa’s Lok Sabha seats will be voted for during the third phase of voting on May 7, with the counting of votes scheduled for June 4.

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